Health Benefits of NAD+ PRO (Nicotinamide Riboside)
Nicotinamide riboside, also commercially known as NAD+ PRO, is not a familiar term with most people but at the rate this anti-aging and healthy supplement has gained popularity, it will soon become a household name.
Why do I say this?
Recent studies have shown that NAD+ PRO does indeed reduce aging, improve brain performance, help in weight loss, and plays a key role in the treatment and management of serious ailments such as diabetes, cancer, Alzheimer’s, asthma, and even acne.
In 2013, researchers from the University of NSW and Harvard University published the findings of a study on the effects of Nicotinamide Riboside on oxidative metabolism on Cell, a popular scientific journal. The study provided detailed insights on how Nicotinamide riboside improves brain performance and acts as an anti-aging agent. NAD+ PRO not only makes you smarter but makes you look and feel younger too. NAD+ Pro is also commonly referred to as an NAD Supplement because its main function is to increase levels of NAD in the body. Nicotinamide Riboside food sources are limited and there simply is not enough of this ingredient in foods to deliver a therapeutic and effective function. Let explore this ingredient in more detail.
So What Exactly is Nicotinamide Riboside?
Nicotinamide riboside is a chemical compound that our bodies produce naturally. It works as a precursor to vitamin B3. It’s a pyridine-nucleoside but don’t bother to know more about that unless you are a chemistry student. What’s important to know is that Nicotinamide riboside is derived from vitamin B3 also known as Niacin. Nicotinamide is produced by the body naturally but you can also get it by eating foods rich in niacin such as cow’s milk, beef, poultry, fish, fortified cereals, whey protein, brewer’s yeast, or by simply taking Nicotinamide or niacin supplements.
The body uses this useful compound to create two coenzymes known as nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). The body uses these two coenzymes in many essential reactions including DNA repair, production of energy, and in regulating cell differentiation among many other functions. Without sufficient amounts of nicotinamide in your diet, some of these essential reactions in your body will be adversely affected.
How NAD+ Benefits Your Body and Overall Health
NAD+ helps your body to regenerate and improve cellular metabolism. It also helps in numerous essential reactions in the body, facilitates cell regeneration to avoid rapid aging, and promotes higher production of energy at cell level.
Here are some of the key benefits of NAD+ to your body:
The process of aging is characterized by increasing levels of fatigue and gradual loss of motivation. Fatigue results from impairment of cellular functions that are essential to the body. NAD+ helps your body to transfer energy derived from the food we eat to important cell functions and fight fatigue. It also helps to eliminate genes that accelerate the aging process. Anti aging is one of many Nicotinamide Riboside benefits.
In the aging process, NAD+ levels in the body gradually decline leading to a reduced number of mitochondria. Mental and physical signs of aging begin to appear when mitochondrial function is impaired. Research has shown that NAD+ plays a key role in slowing down the aging process by protecting tissues and promoting DNA repair to increase your lifespan. If cellular aging is a result of declining levels of NAD+ in the body, then taking this supplement would raise NAD+ levels and extend your lifespan.
Prevention and Treatment of Diabetes
There have been several studies conducted on mice to investigate how nicotinamide helps in the treatment of diabetes. In a 2015 study done in Korea, it was found that a group of mice that were given NAD+ supplements had better glucose tolerance and insulin levels than those who didn’t consume the supplement. Nicotinamide riboside not only reduced blood glucose in mice with Type 2 diabetes but also protected the mice from diabetic nerve problems. It was also found that cholesterol levels in mice that ate the supplement were significantly reduced which showed that NAD+ helps with weight loss too.
Promotes Better Muscle Function
NAD+ helps to restore muscle mass. Studies on mice have shown that consuming the supplement preserves muscle NAD levels and maintain muscle mass and function. Damage to the mitochondria in muscle cells results in a disease called mitochondrial myopathy. The disease causes muscle weakness and other muscle related problems. Oral administration of the supplement on mice suffering from the disease improved mitochondrial function and restored lost muscle mass.
Weight Loss and Obesity
A 2012 Swiss study on the effects of nicotinamide riboside on weight loss and obesity showed that the compound prevents metabolic abnormalities which are caused by the consumption of high-fat diets. The researchers found that nicotinamide boosts production of NAD which helps to fight obesity. It acts as a metabolic furnace that helps the body burn excess fat and calories.
Helps the Body Fight Against Cancer
Nicotinamide riboside has been found to limit or stop the growth of tumour in mice exposed to high levels of oxidative stress. This is mainly because reduced levels of NAD+ synthesis in the body result in DNA damage. The supplement increases NAD+ levels and protects the cells against DNA damage and tumour progression.
Improves Cognitive Function and Prevents Progression of Alzheimer’s Disease
Mount Sinai researchers sought out to analyze how nicotinamide riboside affects Alzheimer’s disease in 2013 by giving a group of mice 250 mg of the supplement every day for 3 months. They found out in memory tests that the mice had improved cognitive function. The treatment also resulted in increased levels of NAD+ in the mice. This demonstrated the positive effect of nicotinamide riboside on cognitive function and on the treatment of Alzheimer’s disease.
Other Health Benefits
Numerous medical studies done on nicotinamide riboside have shed light on its benefits to the body in many ways. Taking the supplement helps in the treatment of asthma, hearing loss which is often a consequence of the aging process, and in the treatment of a common skin condition known as acne vulgaris when it’s combined with zinc and folic acid. The supplement helps to fight acne by reducing the skin’s inflammatory responses that result in lesions and acne.
What Are the Side Effects of Nicotinamide Riboside?
There have been more than 100 studies done on nicotinamide riboside and none of them mention a single effect. The supplement is made from 100% natural ingredients that do not affect the body in any negative way. One of the studies on NAD+ published in 2016 in the Human and Experimental Toxicity Journal stated that the supplement is not genotoxic and doesn’t have adverse side effects on the liver, ovaries, testes, and kidneys.
We’d all love to live forever young but unfortunately, we are all subjected to the aging process. However, you can slow down the process and live a longer healthier life by promoting the natural health of your body’s cells with NAD+ PRO supplement. It not only helps prevent signs of aging but is also effective against serious ailments such as diabetes, cancer, and Alzheimer’s disease. It promotes a raging fast metabolism to burn off excess fat and helps you attain your weight loss goals. The supplement further boosts cell energy production to fight against fatigue and loss of motivation. It’s highly recommended for both young and old users.
The below studies are based on a similar version of the active ingredient Nicotinamide known as Niacinamide. Niacinamide and Nicotinamide have similar benefits and overlapping functions with the main benefit of increasing NAD+.
- Recent study showing this product being effective in treating pre-eclampsia by lowering blood pressure and reducing entothelial dysfunction. The study later identified LPS (endotoxin) as the main culprit in pre-eclampsia and that Niacinamide is an endotoxin antagonist (TLR4).
- Another study showing Nicotinamide mitigating age related decline.
- This study shows potent antiviral activity and the possible treatment of Hepatitis B.
- This study showed Nicotinamide reversing aging in the colon and restoring bowel movements in chronic constipation.
- 2 articles showing mitochondrial stress as a trigger for cancer and Nicotinamide powerfully increases mitochondrial energy production.
- Study showing positive effects of Nicotinamide in treating CVD.
- Article showing Nicotinamide preventing the development of glaucoma.
- New study showing Niacinamide beneficial in treating brain cancer - neuroblastoma.
- Study showing Nicotinamide effective for Parkinson Disease and many other diseases.
- New Cancer study - VEGF and FAO inhibition as effective.
There are many more studies showing the health benefits of Nicotinamide and this places NAD+ Pro as one of the most important supplements to look out for when embarking on an antiaging program or looking to increase health and longevity.
Last Updated: 09/June/2018